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KMID : 1037420190140020034
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Journal of Korean Skull Base Society
2019 Volume.14 No. 2 p.34 ~ p.38
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A case of carcinoid tumor in the middle ear cavity with neurilemmoma in the base of tongue
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Lee Min-Hyeong
Lee Soung-Min
Kim Sang-Yeon
Jun Beom-Cho
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Abstract
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Carcinoid tumors are neuroendocrine tumors which arise from the enterochromaffin cells; the neoplasms grow slowly and are usually found in the gastrointestinal and bronchopulmonary systems. Carcinoid tumors in the middle ear are uncommon since the neuroendocrine cells have not been identified in middle ear mucosa. In this case, a 46-year-old man had tinnitus in right ear for a year. From otoendoscopy findings, we observed a complete perforation of right tympanic membrane and a pinkish mass like lesion at the center of the perforated tympanic membrane. Canal wall up mastoidectomy and tympanoplasty were done, and pathological findings showed cuboidal or columnar cells with small, round, and uniform nuclei; immunohistochemistry demonstrated positive for CD 56 but negative for S-100. Ki-67 proliferation activity was low. While the patient underwent intubation for general anesthesia, a 2 cm polypoid mass was found at right base of tongue. The mass was removed by robot-assisted surgery, and the pathology demonstrated neurilemmoma. The authors report one case of carcinoid tumor that also had neurilemmoma at the same time.
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KEYWORD
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Carcinoid tumor, Ear middle, Neurilemmoma
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